Susceptibility of Ph-positive all to TKI therapy associated with Bcr-Abl rearrangement patterns: a retrospective analysis.
BackgroundTyrosine kinase inhibitors (TKIs) have demonstrated success in the treatment of acute lymphoblastic leukemia (ALL) in patients that express BCR-ABL rearrangements (Philadelphia chromosome [Ph]).The current study aimed to assess the efficacy of TKIs and prognostic factors in the treatment of adults with Ph+-ALL.MethodsIn this multicenter r